ZnO nanowire-FET for charge-based sensing of protein biomolecules

N. M.J. Ditshego; N. A.B. Ghazali; M. Ebert; K. Sun; I. Zeimpekis; P. Ashburn; M. R.R. De Planque; H. M.H. Chong

doi:10.1109/NANO.2015.7388733

ZnO nanowire-FET for charge-based sensing of protein biomolecules

N. M.J. Ditshego, N. A.B. Ghazali, M. Ebert, K. Sun, I. Zeimpekis, P. Ashburn, M. R.R. De Planque, H. M.H. Chong

Electrical, Computer & Telecommunications Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

4 Citations (Scopus)

Abstract

Top-down method was used to fabricate zinc oxide (ZnO) nano wire field effect transistor (NWFET) biosensor. The nanosensor was used to measure the electrical characteristics of lysozyme (LYSO) and bovine serum albumin (BSA) protein solutions in phosphate buffered saline (PBS). The LYSO and BSA proteins are oppositely charged at measurement pH of 7.4. Subthreshold voltage shift of 340 mV and 700 mV due to surface charge effect on the device channel is obtained for the LYSO and BSA solutions respectively. A NWFET sensitivity of 72 % is achieved for the LYSO proteins while the BSA proteins resulted in a sensitivity of 98%.

Original language	English
Title of host publication	IEEE-NANO 2015 - 15th International Conference on Nanotechnology
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	801-804
Number of pages	4
ISBN (Electronic)	9781467381550
DOIs	https://doi.org/10.1109/NANO.2015.7388733
Publication status	Published - Jan 1 2015
Event	15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015 - Rome, Italy Duration: Jul 27 2015 → Jul 30 2015

Other

Other	15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015
Country/Territory	Italy
City	Rome
Period	7/27/15 → 7/30/15

All Science Journal Classification (ASJC) codes

Process Chemistry and Technology
Electrical and Electronic Engineering
Ceramics and Composites
Electronic, Optical and Magnetic Materials
Surfaces, Coatings and Films

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10.1109/NANO.2015.7388733

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Ditshego, N. M. J., Ghazali, N. A. B., Ebert, M., Sun, K., Zeimpekis, I., Ashburn, P., De Planque, M. R. R., & Chong, H. M. H. (2015). ZnO nanowire-FET for charge-based sensing of protein biomolecules. In IEEE-NANO 2015 - 15th International Conference on Nanotechnology (pp. 801-804). [7388733] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NANO.2015.7388733

@inproceedings{bbfa6cdfedc24ea3b2db849ebfc3229d,

title = "ZnO nanowire-FET for charge-based sensing of protein biomolecules",

abstract = "Top-down method was used to fabricate zinc oxide (ZnO) nano wire field effect transistor (NWFET) biosensor. The nanosensor was used to measure the electrical characteristics of lysozyme (LYSO) and bovine serum albumin (BSA) protein solutions in phosphate buffered saline (PBS). The LYSO and BSA proteins are oppositely charged at measurement pH of 7.4. Subthreshold voltage shift of 340 mV and 700 mV due to surface charge effect on the device channel is obtained for the LYSO and BSA solutions respectively. A NWFET sensitivity of 72 % is achieved for the LYSO proteins while the BSA proteins resulted in a sensitivity of 98%.",

author = "Ditshego, {N. M.J.} and Ghazali, {N. A.B.} and M. Ebert and K. Sun and I. Zeimpekis and P. Ashburn and {De Planque}, {M. R.R.} and Chong, {H. M.H.}",

year = "2015",

month = jan,

day = "1",

doi = "10.1109/NANO.2015.7388733",

language = "English",

pages = "801--804",

booktitle = "IEEE-NANO 2015 - 15th International Conference on Nanotechnology",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

address = "United States",

note = "15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015 ; Conference date: 27-07-2015 Through 30-07-2015",

}

Ditshego, NMJ, Ghazali, NAB, Ebert, M, Sun, K, Zeimpekis, I, Ashburn, P, De Planque, MRR & Chong, HMH 2015, ZnO nanowire-FET for charge-based sensing of protein biomolecules. in IEEE-NANO 2015 - 15th International Conference on Nanotechnology., 7388733, Institute of Electrical and Electronics Engineers Inc., pp. 801-804, 15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015, Rome, Italy, 7/27/15. https://doi.org/10.1109/NANO.2015.7388733

TY - GEN

T1 - ZnO nanowire-FET for charge-based sensing of protein biomolecules

AU - Ditshego, N. M.J.

AU - Ghazali, N. A.B.

AU - Ebert, M.

AU - Sun, K.

AU - Zeimpekis, I.

AU - Ashburn, P.

AU - De Planque, M. R.R.

AU - Chong, H. M.H.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - Top-down method was used to fabricate zinc oxide (ZnO) nano wire field effect transistor (NWFET) biosensor. The nanosensor was used to measure the electrical characteristics of lysozyme (LYSO) and bovine serum albumin (BSA) protein solutions in phosphate buffered saline (PBS). The LYSO and BSA proteins are oppositely charged at measurement pH of 7.4. Subthreshold voltage shift of 340 mV and 700 mV due to surface charge effect on the device channel is obtained for the LYSO and BSA solutions respectively. A NWFET sensitivity of 72 % is achieved for the LYSO proteins while the BSA proteins resulted in a sensitivity of 98%.

AB - Top-down method was used to fabricate zinc oxide (ZnO) nano wire field effect transistor (NWFET) biosensor. The nanosensor was used to measure the electrical characteristics of lysozyme (LYSO) and bovine serum albumin (BSA) protein solutions in phosphate buffered saline (PBS). The LYSO and BSA proteins are oppositely charged at measurement pH of 7.4. Subthreshold voltage shift of 340 mV and 700 mV due to surface charge effect on the device channel is obtained for the LYSO and BSA solutions respectively. A NWFET sensitivity of 72 % is achieved for the LYSO proteins while the BSA proteins resulted in a sensitivity of 98%.

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U2 - 10.1109/NANO.2015.7388733

DO - 10.1109/NANO.2015.7388733

M3 - Conference contribution

AN - SCOPUS:84964325865

SP - 801

EP - 804

BT - IEEE-NANO 2015 - 15th International Conference on Nanotechnology

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 15th IEEE International Conference on Nanotechnology, IEEE-NANO 2015

Y2 - 27 July 2015 through 30 July 2015

ER -

ZnO nanowire-FET for charge-based sensing of protein biomolecules

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