Unstable cAMP wave patterns during aggregation of Dictyostelium discoideum cells

N. R. Zaoro, C. B. Tabi, A. S. Etémé, T. C. Kofané

Research output: Contribution to journalArticle

Abstract

Flow-driven formation of unstable patterns of cyclic adenosine monophosphate (cAMP) is investigated in the Martiel-Goldbeter (MG) model. This is predicted via a complex Ginzburg-Landau equation, derived from the MG model, under the so-called modulational instability process. Regions of parameters where patterns exist are discussed analytically and verified numerically. Quasi-periodic waves, spiral seeds and chaotic patterns are found to control information driven in a colony of homogeneously distributed Dictyostelium discoideum cells under the change of the extracellular cAMP degradation rate (ke), the production rate of cAMP (σ) and the advection flow velocity (Vf). Our results suggest that these quantities play a key role in the efficient regulation of communication within an amoeba colony, and the presence of the flow makes it possible to understand pattern formation process among D. discoideum cells under spontaneous fluid flow in their natural environment.

Original languageEnglish
Article number126133
JournalPhysics Letters, Section A: General, Atomic and Solid State Physics
Volume384
Issue number6
DOIs
Publication statusAccepted/In press - Jan 1 2019

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cyclic AMP
cells
amoeba
Landau-Ginzburg equations
advection
fluid flow
seeds
flow velocity
communication
degradation

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

Cite this

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abstract = "Flow-driven formation of unstable patterns of cyclic adenosine monophosphate (cAMP) is investigated in the Martiel-Goldbeter (MG) model. This is predicted via a complex Ginzburg-Landau equation, derived from the MG model, under the so-called modulational instability process. Regions of parameters where patterns exist are discussed analytically and verified numerically. Quasi-periodic waves, spiral seeds and chaotic patterns are found to control information driven in a colony of homogeneously distributed Dictyostelium discoideum cells under the change of the extracellular cAMP degradation rate (ke), the production rate of cAMP (σ) and the advection flow velocity (Vf). Our results suggest that these quantities play a key role in the efficient regulation of communication within an amoeba colony, and the presence of the flow makes it possible to understand pattern formation process among D. discoideum cells under spontaneous fluid flow in their natural environment.",
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Unstable cAMP wave patterns during aggregation of Dictyostelium discoideum cells. / Zaoro, N. R.; Tabi, C. B.; Etémé, A. S.; Kofané, T. C.

In: Physics Letters, Section A: General, Atomic and Solid State Physics, Vol. 384, No. 6, 126133, 01.01.2019.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Unstable cAMP wave patterns during aggregation of Dictyostelium discoideum cells

AU - Zaoro, N. R.

AU - Tabi, C. B.

AU - Etémé, A. S.

AU - Kofané, T. C.

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AB - Flow-driven formation of unstable patterns of cyclic adenosine monophosphate (cAMP) is investigated in the Martiel-Goldbeter (MG) model. This is predicted via a complex Ginzburg-Landau equation, derived from the MG model, under the so-called modulational instability process. Regions of parameters where patterns exist are discussed analytically and verified numerically. Quasi-periodic waves, spiral seeds and chaotic patterns are found to control information driven in a colony of homogeneously distributed Dictyostelium discoideum cells under the change of the extracellular cAMP degradation rate (ke), the production rate of cAMP (σ) and the advection flow velocity (Vf). Our results suggest that these quantities play a key role in the efficient regulation of communication within an amoeba colony, and the presence of the flow makes it possible to understand pattern formation process among D. discoideum cells under spontaneous fluid flow in their natural environment.

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