Reaction of ethyl acetoacetate and 2'-hydroxychalcones

Efficient route to 9-aryl-6H-benzo[c]chromen-6-ones

Ishmael B. Masesane, Ofentse Mazimba

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The reaction of ethyl acetoacetate and 2'-hydroxychalcones under atmospheric air to furnish a series of functionalized 6H-benzo[c]chromen-6-ones in moderate yields is reported. The reaction proceeds through trans-esterification, intra-molecular Michael addition, Robinson annulation and oxidative aromatization.

Original languageEnglish
Pages (from-to)289-294
Number of pages6
JournalBulletin of the Chemical Society of Ethiopia
Volume28
Issue number2
DOIs
Publication statusPublished - Jan 1 2014

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Aromatization
Transesterification
Air
ethyl acetoacetate
2'-hydroxychalcone
6H-benzo(c)chromen-6-one

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

Cite this

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Reaction of ethyl acetoacetate and 2'-hydroxychalcones : Efficient route to 9-aryl-6H-benzo[c]chromen-6-ones. / Masesane, Ishmael B.; Mazimba, Ofentse.

In: Bulletin of the Chemical Society of Ethiopia, Vol. 28, No. 2, 01.01.2014, p. 289-294.

Research output: Contribution to journalArticle

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