Programmed cell death

Genes involved in signaling, regulation, and execution in plants and animals

Gaolathe Rantong, Arunika H.L.A.N. Gunawardena

Research output: Contribution to journalReview article

18 Citations (Scopus)

Abstract

Programmed cell death (PCD) is a suicide mechanism adopted by multicellular organisms that is essential for development and resistance to different forms of stress. In plants, PCD is involved from embryogenesis to death of the whole plant. PCD is genetically regulated and the molecular pathways involved in different forms of this process in animals are relatively more understood than in plants. At the morphological level, apoptosis, one of the forms of PCD in animals, and plant PCD have some similarities such as cell shrinkage, shrinkage of the nucleus, and DNA fragmentation. Because morphological characteristics are a product of the genetically encoded PCD mechanism, it is of interest to figure out how much of the apoptotic pathway is shared with plant PCD in terms of the genes involved. Evidence of some level of similarities has been gathered in the last decade, supporting conservation during signaling, regulation, and execution of apoptosis and plant PCD. A continued search into the genomes of plants has provided insights about homologues of apoptosis genes present in plants, and functional analysis provides evidence about which genes are carrying out similar roles during apoptosis and plant PCD. This review is aimed at updating on the progress of plant PCD mechanism research and highlighting some of the similarities and differences between plant and mammalian PCD mechanisms, with special focus on the commonalities.

Original languageEnglish
Pages (from-to)193-210
Number of pages18
JournalBotany
Volume93
Issue number4
DOIs
Publication statusPublished - Dec 1 2015

Fingerprint

apoptosis
gene
animal
animals
genes
regulation
shrinkage
suicide
fragmentation
DNA fragmentation
genome
DNA
embryogenesis
death

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Ecology
  • Plant Science

Cite this

@article{75248c4159cb48aa81447cb55ea55541,
title = "Programmed cell death: Genes involved in signaling, regulation, and execution in plants and animals",
abstract = "Programmed cell death (PCD) is a suicide mechanism adopted by multicellular organisms that is essential for development and resistance to different forms of stress. In plants, PCD is involved from embryogenesis to death of the whole plant. PCD is genetically regulated and the molecular pathways involved in different forms of this process in animals are relatively more understood than in plants. At the morphological level, apoptosis, one of the forms of PCD in animals, and plant PCD have some similarities such as cell shrinkage, shrinkage of the nucleus, and DNA fragmentation. Because morphological characteristics are a product of the genetically encoded PCD mechanism, it is of interest to figure out how much of the apoptotic pathway is shared with plant PCD in terms of the genes involved. Evidence of some level of similarities has been gathered in the last decade, supporting conservation during signaling, regulation, and execution of apoptosis and plant PCD. A continued search into the genomes of plants has provided insights about homologues of apoptosis genes present in plants, and functional analysis provides evidence about which genes are carrying out similar roles during apoptosis and plant PCD. This review is aimed at updating on the progress of plant PCD mechanism research and highlighting some of the similarities and differences between plant and mammalian PCD mechanisms, with special focus on the commonalities.",
author = "Gaolathe Rantong and Gunawardena, {Arunika H.L.A.N.}",
year = "2015",
month = "12",
day = "1",
doi = "10.1139/cjb-2014-0152",
language = "English",
volume = "93",
pages = "193--210",
journal = "Botany",
issn = "1916-2790",
publisher = "National Research Council of Canada",
number = "4",

}

Programmed cell death : Genes involved in signaling, regulation, and execution in plants and animals. / Rantong, Gaolathe; Gunawardena, Arunika H.L.A.N.

In: Botany, Vol. 93, No. 4, 01.12.2015, p. 193-210.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Programmed cell death

T2 - Genes involved in signaling, regulation, and execution in plants and animals

AU - Rantong, Gaolathe

AU - Gunawardena, Arunika H.L.A.N.

PY - 2015/12/1

Y1 - 2015/12/1

N2 - Programmed cell death (PCD) is a suicide mechanism adopted by multicellular organisms that is essential for development and resistance to different forms of stress. In plants, PCD is involved from embryogenesis to death of the whole plant. PCD is genetically regulated and the molecular pathways involved in different forms of this process in animals are relatively more understood than in plants. At the morphological level, apoptosis, one of the forms of PCD in animals, and plant PCD have some similarities such as cell shrinkage, shrinkage of the nucleus, and DNA fragmentation. Because morphological characteristics are a product of the genetically encoded PCD mechanism, it is of interest to figure out how much of the apoptotic pathway is shared with plant PCD in terms of the genes involved. Evidence of some level of similarities has been gathered in the last decade, supporting conservation during signaling, regulation, and execution of apoptosis and plant PCD. A continued search into the genomes of plants has provided insights about homologues of apoptosis genes present in plants, and functional analysis provides evidence about which genes are carrying out similar roles during apoptosis and plant PCD. This review is aimed at updating on the progress of plant PCD mechanism research and highlighting some of the similarities and differences between plant and mammalian PCD mechanisms, with special focus on the commonalities.

AB - Programmed cell death (PCD) is a suicide mechanism adopted by multicellular organisms that is essential for development and resistance to different forms of stress. In plants, PCD is involved from embryogenesis to death of the whole plant. PCD is genetically regulated and the molecular pathways involved in different forms of this process in animals are relatively more understood than in plants. At the morphological level, apoptosis, one of the forms of PCD in animals, and plant PCD have some similarities such as cell shrinkage, shrinkage of the nucleus, and DNA fragmentation. Because morphological characteristics are a product of the genetically encoded PCD mechanism, it is of interest to figure out how much of the apoptotic pathway is shared with plant PCD in terms of the genes involved. Evidence of some level of similarities has been gathered in the last decade, supporting conservation during signaling, regulation, and execution of apoptosis and plant PCD. A continued search into the genomes of plants has provided insights about homologues of apoptosis genes present in plants, and functional analysis provides evidence about which genes are carrying out similar roles during apoptosis and plant PCD. This review is aimed at updating on the progress of plant PCD mechanism research and highlighting some of the similarities and differences between plant and mammalian PCD mechanisms, with special focus on the commonalities.

UR - http://www.scopus.com/inward/record.url?scp=84927137208&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84927137208&partnerID=8YFLogxK

U2 - 10.1139/cjb-2014-0152

DO - 10.1139/cjb-2014-0152

M3 - Review article

VL - 93

SP - 193

EP - 210

JO - Botany

JF - Botany

SN - 1916-2790

IS - 4

ER -