Pharmacology and phytochemistry studies in Peltophorum africanum

Research output: Contribution to journalArticle

Abstract

Peltophorum africanum Sond is an ethnomedicinal plant in the family Fabaceae. This literature report captures information about the ethnomedical uses, pharmacology and phytochemistry of P. africanum within the last four decades. The literature surveyed revealed the presence of different types of polyphenols whose content was higher in the bark and roots than the leaves. The plant polar extracts are rich in phenolic compounds and shows high antioxidant properties. The root and stem extracts are active against bacteria, parasites and HIV. There were no reports on the quality control of P. africanum as a herbal drug, nor a systematic identification of which phytochemicals are responsible for most of the pharmacological activities. Betulinic acid found in the bark is a known anti HIV agent. The reports on the pharmacological functions and the phytochemical studies which were started based on the traditional uses and botanical information justify the ethnomedicinal uses of the tree.
Original languageEnglish
Pages (from-to)145-153
Number of pages9
JournalBulletin of Faculty of Pharmacy, Cairo University
Volume52
Issue number1
DOIs
Publication statusPublished - 2014

Fingerprint

plant biochemistry
pharmacology
phytopharmaceuticals
bark
herbal medicines
extracts
Fabaceae
quality control
phenolic compounds
polyphenols
antioxidants
parasites
stems
bacteria
Peltophorum africanum
leaves

Cite this

@article{2c8170bcd6cd49eda5146794e752a616,
title = "Pharmacology and phytochemistry studies in Peltophorum africanum",
abstract = "Peltophorum africanum Sond is an ethnomedicinal plant in the family Fabaceae. This literature report captures information about the ethnomedical uses, pharmacology and phytochemistry of P. africanum within the last four decades. The literature surveyed revealed the presence of different types of polyphenols whose content was higher in the bark and roots than the leaves. The plant polar extracts are rich in phenolic compounds and shows high antioxidant properties. The root and stem extracts are active against bacteria, parasites and HIV. There were no reports on the quality control of P. africanum as a herbal drug, nor a systematic identification of which phytochemicals are responsible for most of the pharmacological activities. Betulinic acid found in the bark is a known anti HIV agent. The reports on the pharmacological functions and the phytochemical studies which were started based on the traditional uses and botanical information justify the ethnomedicinal uses of the tree.",
author = "Ofentse Mazimba",
year = "2014",
doi = "10.1016/j.bfopcu.2014.01.001",
language = "English",
volume = "52",
pages = "145--153",
journal = "Bulletin of Faculty of Pharmacy, Cairo University",
issn = "1110-0931",
publisher = "Faculty of Pharmacy, Cairo University",
number = "1",

}

Pharmacology and phytochemistry studies in Peltophorum africanum. / Mazimba, Ofentse.

In: Bulletin of Faculty of Pharmacy, Cairo University, Vol. 52, No. 1, 2014, p. 145-153.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Pharmacology and phytochemistry studies in Peltophorum africanum

AU - Mazimba, Ofentse

PY - 2014

Y1 - 2014

N2 - Peltophorum africanum Sond is an ethnomedicinal plant in the family Fabaceae. This literature report captures information about the ethnomedical uses, pharmacology and phytochemistry of P. africanum within the last four decades. The literature surveyed revealed the presence of different types of polyphenols whose content was higher in the bark and roots than the leaves. The plant polar extracts are rich in phenolic compounds and shows high antioxidant properties. The root and stem extracts are active against bacteria, parasites and HIV. There were no reports on the quality control of P. africanum as a herbal drug, nor a systematic identification of which phytochemicals are responsible for most of the pharmacological activities. Betulinic acid found in the bark is a known anti HIV agent. The reports on the pharmacological functions and the phytochemical studies which were started based on the traditional uses and botanical information justify the ethnomedicinal uses of the tree.

AB - Peltophorum africanum Sond is an ethnomedicinal plant in the family Fabaceae. This literature report captures information about the ethnomedical uses, pharmacology and phytochemistry of P. africanum within the last four decades. The literature surveyed revealed the presence of different types of polyphenols whose content was higher in the bark and roots than the leaves. The plant polar extracts are rich in phenolic compounds and shows high antioxidant properties. The root and stem extracts are active against bacteria, parasites and HIV. There were no reports on the quality control of P. africanum as a herbal drug, nor a systematic identification of which phytochemicals are responsible for most of the pharmacological activities. Betulinic acid found in the bark is a known anti HIV agent. The reports on the pharmacological functions and the phytochemical studies which were started based on the traditional uses and botanical information justify the ethnomedicinal uses of the tree.

U2 - 10.1016/j.bfopcu.2014.01.001

DO - 10.1016/j.bfopcu.2014.01.001

M3 - Article

VL - 52

SP - 145

EP - 153

JO - Bulletin of Faculty of Pharmacy, Cairo University

JF - Bulletin of Faculty of Pharmacy, Cairo University

SN - 1110-0931

IS - 1

ER -