Modulated charge patterns and noise effect in a twisted DNA model with solvent interaction

C. B. Tabi, A. Dang Koko, R. Oumarou Doko, H. P. Ekobena Fouda, T. C. Kofané

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

We modify the Peyrard-Bishop-Holstein model and bring out the influence of the torsion and solvent interactions on charge transport in DNA. Through the linear stability analysis, we detect regions of instability and we compare the results with those of the standard Peyrard-Bishop-Holstein model. There are two regimes where modulated charge patterns can occur: the undertwisted and the overtwisted conformations. Numerical simulations are used to confirm our analytical predictions. Charge patterns are obtained and propagate more easily in an overwinded helix than in an underwinded one. The effects of dissipation and thermal fluctuations are also studied, which confirm the robustness of the obtained modulated patterns. On the one hand, we argue that in the absence of twisting, temperature can lead to the breaking of the hydrogen bonds between bases and prevent charges from propagating. On the other hand, when the molecule is overtwisted, the solvent and the temperature will rather enhance charge spreading patterns with random features.

Original languageEnglish
Pages (from-to)498-509
Number of pages12
JournalPhysica A: Statistical Mechanics and its Applications
Volume442
DOIs
Publication statusPublished - Jan 15 2016

Fingerprint

deoxyribonucleic acid
Charge
Interaction
interactions
Charge Transport
Hydrogen Bonds
Linear Stability Analysis
twisting
Helix
Conformation
Model
helices
torsion
Torsion
Dissipation
dissipation
Molecules
Fluctuations
hydrogen bonds
Robustness

All Science Journal Classification (ASJC) codes

  • Statistics and Probability
  • Condensed Matter Physics

Cite this

Tabi, C. B. ; Dang Koko, A. ; Oumarou Doko, R. ; Ekobena Fouda, H. P. ; Kofané, T. C. / Modulated charge patterns and noise effect in a twisted DNA model with solvent interaction. In: Physica A: Statistical Mechanics and its Applications. 2016 ; Vol. 442. pp. 498-509.
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Modulated charge patterns and noise effect in a twisted DNA model with solvent interaction. / Tabi, C. B.; Dang Koko, A.; Oumarou Doko, R.; Ekobena Fouda, H. P.; Kofané, T. C.

In: Physica A: Statistical Mechanics and its Applications, Vol. 442, 15.01.2016, p. 498-509.

Research output: Contribution to journalArticle

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AU - Tabi, C. B.

AU - Dang Koko, A.

AU - Oumarou Doko, R.

AU - Ekobena Fouda, H. P.

AU - Kofané, T. C.

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