There are several geological, geochemical and geophysical evidences, which corroborate reconstruction of Gondwanaland and juxtaposition of India and Antarctica. Petrology of the Precambrian mafic dykes of East Antarctica and Central-East India also support juxtaposition of India and Antarctica. Mafic dykes of different generations are emplaced in the Archaean granite gneisses of these regions. These dykes appear to be an important tool to support juxtaposition of India and Antarctica. Geological and petrological data of the Central-East India Precambrian mafic dykes suggest four episodes of mafic magmatism in the region - three tholeiitic and one noritic (?). Similarly, East Antarctica also comprises four dyke suites, emplaced during three distinct periods. These suites are 2.4 Ga meta-tholeiites, 2.4 Ga high-Mg tholeiites, 1.8 Ga dolerites and 1.2–1.4 Ga dolerites. Geochemical compositions of these mafic dykes are compared and they show good relationships with each other. Similarities in petrological and geochemical characteristics of Precambrian mafic dykes of East Antarctica and Central-East India strongly support juxtaposition of these two continents.