Behavior and toxicity of antimony in the short-tailed field vole (Microtus agrestis)

N. Ainsworth, J. A. Cooke, M. S. Johnson

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Laboratory experiments were undertaken to study uptake and retention of antimony and to investigate whether the elevated organ antimony concentrations found previously in a population of Microtus agrestis at a contaminated site could cause harmful effects. Antimony trioxide in the diet produced elevated organ concentrations, but even in a 60-day experiment no harmful effects were evident. An equilibrium between uptake and excretion of antimony seemed to be rapidly established and progressive increases in organ concentrations did not occur. When dietary intake was terminated antimony was rapidly cleared. Comparison of findings from the laboratory and field suggested that inhalation was an additional route of intake in the field. It seems that present levels of antimony are unlikely to cause toxic effects in the wild population.

Original languageEnglish
Pages (from-to)165-170
Number of pages6
JournalEcotoxicology and Environmental Safety
Volume21
Issue number2
DOIs
Publication statusPublished - Jan 1 1991

Fingerprint

Antimony
Arvicolinae
antimony
Toxicity
toxicity
Poisons
Nutrition
Inhalation
Population
wild population
excretion
Experiments
Diet
diet
organ

All Science Journal Classification (ASJC) codes

  • Environmental Science(all)
  • Environmental Chemistry
  • Earth and Planetary Sciences(all)

Cite this

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abstract = "Laboratory experiments were undertaken to study uptake and retention of antimony and to investigate whether the elevated organ antimony concentrations found previously in a population of Microtus agrestis at a contaminated site could cause harmful effects. Antimony trioxide in the diet produced elevated organ concentrations, but even in a 60-day experiment no harmful effects were evident. An equilibrium between uptake and excretion of antimony seemed to be rapidly established and progressive increases in organ concentrations did not occur. When dietary intake was terminated antimony was rapidly cleared. Comparison of findings from the laboratory and field suggested that inhalation was an additional route of intake in the field. It seems that present levels of antimony are unlikely to cause toxic effects in the wild population.",
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Behavior and toxicity of antimony in the short-tailed field vole (Microtus agrestis). / Ainsworth, N.; Cooke, J. A.; Johnson, M. S.

In: Ecotoxicology and Environmental Safety, Vol. 21, No. 2, 01.01.1991, p. 165-170.

Research output: Contribution to journalArticle

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